Posology: Adults: The individual dosage and the interval between injections should be tailored to the patient's condition.
Fluanxol Depot 20mg/ml: In the maintenance treatment the dosage range would normally be 20-40 mg (1-2 ml) every 2-4 weeks depending on the response.
Some patients may need higher doses or a shorter interval between the injections. Fluanxol Depot 20mg/ml is unsuitable for patients who require a sedative effect. If volumes larger than 2-3 ml of the 20 mg/ml solution are required the more concentrated solution (Fluanxol Depot 100mg/ml) should be preferred.
When changing the medication from oral Fluanxol to maintenance treatment with Fluanxol Depot the following guidelines should be used: x mg p.o. daily corresponds to 4x mg decanoate every 2 weeks; x mg p.o. daily corresponds to 8x mg decanoate every 4 weeks.
Continue to administer Fluanxol for the first week after the initial injection, then gradually reduce the dosage.
Subsequent doses and intervals between injections should be adjusted according to the patient's response.
Elderly patients: Caution must be exercised in elderly patients.
Renal impairment: Can be given in normal doses.
Liver impairment: Caution must be exercised in patients with hepatic impairment. Careful dosing and, if possible, a serum level determination is advisable.
Children: Flupentixol decanoate is not recommended for use in children due to lack of clinical experience.
Method of administration: Flupentixol decanoate is administered by intramuscular injection into the upper outer quadrant of the gluteal region. Injection volumes exceeding 2 ml should be distributed between two injection sites. Local tolerability is good.